Albumin and Edestin

What is Albumin

Albumin is the main blood protein found in blood plasma. It is primarily used by the body to transport various nutrients or drugs and also to maintain oncotic pressure and balance in the internal environment.

If an acute condition occurs and the body cannot obtain basic building blocks for the production of body proteins in a standard way, it begins to obtain them from Albumin.

However, this can quickly lead to a significant disruption of the body’s internal environment (homeostasis), which can result in rapid organ failure.

What is Edestin?

It bears a striking resemblance to Albumin. For several decades, scientists have been interested in the interchangeability of these proteins, especially in medicine.

Together with the German company HealChain GmbH, we have conducted an exhaustive analysis of what the global professional community knows about Edestin. We used the Ontosight platform, which works with artificial intelligence. We mapped the results of more than 92,000 expert studies. This gives us a detailed overview of Edestin’s known properties.

We have verified that there is no other research team or organization worldwide that is dedicated to the development or preparation of blood plasma substitute from Edestin. Therefore, our project is unique and we are exceptional in this area. Our work is not only pioneering but also entirely original.

Edestin Structure

Edestin Types

There are three types of edestin. We refer to them as edestin1, edestin2, edestin3. The antigenic sites of edestin1 are more accessible than those of edestin2, while the antigenic sites of edestin3 are inaccessible to antibodies. Albumin and edestin3 are more immunologically compatible.

edestin 1
(511 AA)

edestin 2
(491 AA)

edestin 3
(493 AA)

Albumin vs. Edestin



Albumin and edestin are both globular proteins.

Edestin shows better antioxidant and ACE inhibitory activity than albumin.

The structure of both edestin and albumin is highly stable at pH 5.8-7.8.

Edestin (HPHs) exhibits anti-inflammatory activity with the ability to bind zinc. Albumin has similar activity.

The antigenicity of edestin is 7%, which is slightly higher than that of albumin, which has an antigenicity of 6% of the surface of the molecule.

Edestin will most likely provide a volume expansion of less than 80%, similar to albumin.

Both proteins are rich in essential amino acids.